Key Takeaways
- Hormones play a big role in how we feel and can affect our mood and emotions.
- Seeing a doctor like an endocrinologist can help you manage hormone problems that affect your mental health.
- Lifestyle changes, like getting enough sleep and exercising, can improve your hormone balance and mental wellness.
Hormones are chemical messengers secreted by our endocrine glands. They influence many aspects of our body’s functioning, including metabolism, growth, sexual health, and reproductive system functioning. Our mental health is strongly impacted by hormones because hormones have a major role to play in the regulation of moods and emotions.
Almost all of your hormones affect your mood, emotions, and mental health in one way or another.
Let’s take a closer look at how hormones influence our mental health, including which particular hormones are at play, what happens when hormones fluctuate or become imbalanced, and how to manage any hormone changes you may be experiencing.
What Are the Main Hormones?
Hormones are secreted by a group of endocrine glands found throughout the body. These glands include:
- Pituitary gland
- Thymus
- Pineal gland
- Thyroid gland
- Pancreas
- Adrenal glands
- Ovaries
- Testes
Almost all of your hormones affect your mood, emotions, and mental health in one way or another. Here’s what to know about some of the hormones that have the most impact on your mental health.
Serotonin
Serotonin is a neurotransmitter that helps regulate mood and behavior and also supports memory function. Imbalances in serotonin are believed to contribute to conditions such as depression, anxiety disorders, post-traumatic stress disorder, and obsessive-compulsive disorder.
Dopamine
Dopamine, a neurotransmitter, and its receptors throughout the body play a crucial role in regulating mood and emotions. It is also involved in the brain’s reward system.
Cortisol
Cortisol is a steroid hormone that helps manage stress in the body. It activates the body’s stress response when you face challenging or threatening situations.
When triggered, cortisol engages the “fight or flight” system, leading to physical reactions such as increased heart rate and rapid breathing.
Thyroid Hormone
Thyroid hormones are secreted by your thyroid gland, a butterfly-shaped gland in your neck. Thyroid hormones influence metabolism, your heart, your lungs, and your muscles.
Too little or too much thyroid hormone can cause symptoms of depression and anxiety.
Sex Hormones
The main sex hormones for women are estrogen and progesterone, which fluctuate and change throughout the menstrual cycle, during pregnancy, and later in life, when menopause occurs.
These hormones greatly affect mood, emotions, and sexuality. Testosterone is the main male hormone and also affects moods, behavior, and sexual feelings.
The Impact of Hormonal Changes on Mental Health
Your hormones are constantly changing throughout your day and throughout your life. Hormones guide your growth and development in childhood and adolescence. In women, they influence menstruation, and reproduction. Stress in your life impacts levels of hormones like cortisol.
Nina Vasan, MD, psychiatrist
Hormones can have a big impact on your mental health.
— Nina Vasan, MD, psychiatrist
Hormonal changes throughout life can affect your emotions and mental well-being. “Hormones can have a big impact on your mental health,” says Nina Vasan, MD, psychiatrist and chief medical officer at Real. According to Dr. Vasan, the hormonal shifts during the menstrual cycle can lead to mood swings and irritability. She also notes that during menopause, decreasing estrogen and progesterone levels may cause anxiety and depression.
Thyroid hormone fluctuations can also significantly affect mental health. “Too much or too little thyroid hormone can cause anxiety,” she describes. “Hormones have a direct connection to how we feel mentally and physically.”
Hormonal Imbalances and Mental Health
“The ultimate goal of the endocrine glands is to maintain a balanced state of ‘homeostasis,’” explains Aron Tendler, MD, BrainsWay chief medical officer. “When this is lost, the endocrine glands will drive to restore it.”
Homeostasis
Homeostasis is a state of balance needed throughout the body’s systems in order for it to survive and function properly.
During times of hormonal imbalance, you may experience various bodily changes, including mental health symptoms, says Dr. Tendler. “This is why patients with endocrinological disorders have mental health symptoms,” he says.
Examples of hormonal imbalances that affect mental health include:
- Thyroid conditions, like hypothyroidism (too little thyroid hormone), which is usually linked to low mood or depression, or hyperthyroidism (too much thyroid hormone), which is usually linked to irritability and anxiety
- Premenstrual syndrome and premenstrual dysphoric disorder (PMDD), which are caused by hormonal fluctuations and are linked to significant mood swings and emotional upheaval
- Postpartum depression, a serious mood disorder, which is linked to rapidly changing hormones during and after childbirth
- Perimenopause and menopause, which are characterized by severe mood swings, depression, and anxiety, are caused by significant drops in the hormone estrogen
Managing Hormonal Changes to Improve Mental Well-Being
If you suspect your hormones are impacting your mental health, it’s best to visit a healthcare provider to get a diagnosis and discuss treatment options. This may be your primary care provider, your OB-GYN, or a psychiatrist. Dr. Tendler says that often, a type of doctor called an endocrinologist is the recommended physician to see when you are dealing with a potential hormone issue.
When treating hormones changes and mental health, it’s usually best to take a holistic approach, addressing lifestyle changes, prescribing medication, and employing different therapy modalities to manage your symptoms.
Here’s what to know.
Lifestyle Changes
“Life changes can go a long way to improve hormone issues and, in turn, improve wellness,” explains Dr. Vasan. She recommends a few main areas to focus on in order to bring your hormones into homeostasis:
- Make sure to get enough sleep
- Add more exercise into your daily routine
- Stick to a diet that focuses on whole foods, rather than processed foods
- Make sure to talk about your feelings, including starting therapy when needed
Medications
The types of medication used to treat mental health issues brought on by hormones or hormone imbalances vary based on which hormones and bodily systems are impacted.
“Medications can help alleviate the effects of hormone imbalance,” says Dr. Vason. For example, she says, hormone replacement therapy (HRT) is a helpful way to address some of the mood changes that occur during menopause and perimenopause.
In addition to HRT, other medications used to address hormonal imbalances include:
- Thyroid medications to address hypothyroidism and hyperthyroidism
- Birth control pills, antidepressants, and anti-anxiety medication to address symptoms of PMS
- Antidepressants to address postpartum depression
Therapy Options
As with medications, therapy options for hormonal imbalances will depend on the symptoms you’re experiencing.
Some options may include:
- Depression symptoms are usually treated with cognitive behavioral therapy, behavioral therapy, systemic therapy, and various forms of psychoanalysis
- Anxiety is often treated with cognitive behavioral therapy, exposure therapy, and acceptance and commitment therapy
- PMS may be treated with cognitive behavioral therapy and various types of relaxation therapies, like meditation and breathing exercises
Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
National Library of Medicine. Hormones.
Bamalan OA, Moore MJ, Al Khalili Y. Physiology, Serotonin. StatPearls Publishing.
Bhatia A, Lenchner JR, Saadabadi A. Biochemistry, Dopamine Receptors. StatPearls Publishing.
Thau L, Gandhi J, Sharma S. Physiology, Cortisol. StatPearls Publishing.
Shahid MA, Ashraf MA, Sharma S. Physiology, Thyroid Hormone. StatPearls Publishing.
Brzezinski-Sinai NA, Brzezinski A. Schizophrenia and Sex Hormones: What Is the Link? Frontiers in Psychiatry. 2020;11:693. doi:10.3389/fpsyt.2020.00693
Silver NE. Mood Changes During Perimenopause Are Real. Here’s What to Know. American College of Obstetricians and Gynecologists.
Kamble MT, Nandedkar PD, Dharme PV, et al. Thyroid function and mental disorders: an insight into the complex interaction. Journal of Clinical and Diagnostic Research. 2013;7(1):11-14. doi:10.7860/JCDR/2012/4861.2656
Gudipally PR, Sharma GK. Premenstrual Syndrome. StatPearls Publishing.
Høgh S, Hegaard HK, Renault KM, et al. Short-term oestrogen as a strategy to prevent postpartum depression in high-risk women: protocol for the double-blind, randomised, placebo-controlled MAMA clinical trial. BMJ Open. 2021;11:e052922. doi:10.1136/bmjopen-2021-052922
Institute for Quality and Efficiency in Health Care (IQWiG). Premenstrual syndrome: Treatment for PMS.
American College of Obstetricians and Gynecologists. Premenstrual Syndrome (PMS).
Institute for Quality and Efficiency in Health Care (IQWiG). Treatments for depression.
National Institute of Mental Health. Anxiety Disorders.
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