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    Home»Tips»How to Manage Inactive SPMS
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    How to Manage Inactive SPMS

    By November 7, 2025No Comments1 Min Read
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    How to Manage Inactive SPMS
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    If you have inactive secondary progressive multiple sclerosis (SPMS), you know firsthand that it can be difficult to manage. Unlike active SPMS, where you see clear signs of new relapses, inactive SPMS progresses gradually, with worsening symptoms sometimes going unnoticed and untreated.

    What’s more, there are no medications that treat this form of MS specifically — but hopefully not for long. Several medications are being studied in clinical trials and reviewed by the U.S. Food and Drug Administration for their potential to slow the progression of inactive SPMS.

    [1]

    [2]

    While researchers work to close this treatment gap, there are other ways to manage inactive SPMS symptoms and feel better in your day-to-day life. “While there isn’t any disease-specific therapy, we still want to make sure we’re treating your symptoms and doing everything we can to improve your quality of life,” says Paunel Agyei, MD, a board-certified neurologist for the Mellen Program for MS at Cleveland Clinic in Weston, Florida.

    Your care team can work with you to find symptom-targeted medications, therapies, and lifestyle habits to help you feel and move better. Keep reading to learn more about your options.

    Inactive Manage SPMS
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