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    Home»Recipes»20+ High Protein Casseroles
    Recipes

    20+ High Protein Casseroles

    By December 24, 2025No Comments8 Mins Read
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    20+ High Protein Casseroles
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    Photographer: Jen Causey, Food Stylist: Julian Hensarling, Prop Stylist: Julia Bayless

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    Getting enough protein is key to supporting a wide range of health goals, from building strength to supporting your immune system. Whether you’re working to increase energy levels or maintain muscle and bone strength, these casseroles are great options since they’re packed with at least 15 grams of protein per serving. Plus they all have at least four-star reviews from EatingWell readers, so you know they’re bound to be delicious! Recipes like Unstuffed Zucchini Casserole or Creamy Lemon-Dill Rotisserie Chicken Noodle Casserole make for delicious dinners that will keep you satisfied.

    Love these recipes? Join MyRecipes—your personal home for recipes—to easily save and organize your favorites, plus thousands more, in one convenient place.

    Honey-Garlic Chicken Casserole

    Photographer: Stacy k. Allen, Props: Christina Brockman, Food Stylist: Lauren Odum

    This honey-garlic chicken casserole is the perfect option for when you want a protein-packed stir-fry. To keep prep to a minimum, we use precooked brown rice. Look for it in pouches at the store or whip up this one-pot meal when you have leftovers to spare.

    Pizza Pasta Casserole

    Photographer: Fred Hardy, Food Stylist: Jennifer Wendorf, Prop Stylist: Lydia Purcell

    This easy, toss-together casserole offers all the flavors of a pepperoni pizza, with fusilli pasta absorbing the rich tomato sauce while mingling with gooey melted cheese and meaty pepperoni slices. For a meatless option, simply replace the pepperoni with sliced mushrooms and bell peppers.

    Creamy Lemon-Dill Rotisserie Chicken Noodle Casserole

    Photographer: Jen Causey, Food Stylist: Julian Hensarling, Prop Stylist: Julia Bayless

    Imagine this simple recipe as the casserole version of classic chicken noodle soup! High-quality broth or homemade chicken stock enhances the flavor along with fresh, grassy notes of dill.

    Cheesy Beef & Black Bean Skillet Casserole

    Photographer: Jennifer Causey, Food Stylist: Julian Hensarling, Prop Stylist: Christina Daley

    In this taco-inspired casserole, the corn tortillas crisp up under the broiler, adding crunch to go with the creamy filling. If you enjoy a bit of spiciness, opt for hot salsa or chipotle salsa for some smoky undertones. 

    Pesto Tuna Noodle Casserole

    Photographer: Grant Webster, Food Stylist: Holly Dreesman, Prop Stylist: Lexi Juhl

    A creamy pesto sauce with sweet shallots and wilted spinach gives a light and bright spin to classic tuna noodle casserole. Using refrigerated pesto is recommended for its fresh flavor, which enhances the overall dish.

    Chicken Piccata Casserole

    Photographer: Morgan Hunt Glaze, Prop Stylist: Shell Royster, Food Stylist Jennifer Wendorf

    This protein-packed casserole brings all the flavors of classic chicken piccata together in one dish. Cooking the lemon slices in butter mellows their bite and helps jump-start the lemony flavor of the dish.

    Cheeseburger Casserole

    Photographer: Rachel Marek, Food stylist: Holly Dreesman, Prop stylist: Gabriel Greco

    If you love a classic cheeseburger with all the fixings, you’ll love this casserole. Shredded lettuce offers a refreshing crunch, but feel free to mix it up with another green like spinach or kale, or top with Swiss cheese and sautéed mushrooms for a different spin.

    Creamy Chicken & Penne alla Vodka Casserole with Peas

    Photographer: Jake Sternquist, Food stylist: Annie Probst, Prop stylist: Gabriel Greco

    This cheesy chicken pasta casserole is perfect for a busy weeknight when you need a fast and easy dinner with minimal cleanup. 

    Spanakopita-Inspired Chicken & White Bean Casserole

    Photographer: Carson Downing, Food Stylist: Annie Probst, Prop Stylist: Joseph Wanek

    This is a fun take on spanakopita, with a creamy feta-and-spinach filling and a crispy phyllo topping. Chicken and white beans pack in the protein. Any white beans, such as cannellini, garbanzo or navy beans, work well here.

    Anti-Inflammatory Lemony Salmon & Orzo Casserole

    Stacy Allen

    This lemony casserole is a one-dish dinner that’s packed with omega-3 fatty acids. Salmon sits on top of an orzo mixture that bakes in the oven and absorbs all the bright, lemony flavors while it cooks.

    Creamed Spinach & Chicken Casserole

    Photographer: Fred Hardy, Food Stylist: Ruth Blackburn, Prop Stylist: Shell Royster

    Creamed spinach and chicken combine in this crowd-pleasing, comforting casserole. Crushed red pepper packs some heat, so add less or leave it out completely if you want a milder version. 

    Stuffed Pepper Casserole

    Photographer Victor Protasio, Food Stylist Jennifer Wendorf, Prop Stylist Julia Bayless

    You won’t be stuffing any peppers for this stuffed pepper casserole, but you will be enjoying the sweet and smoky combination of flavors coming from bell peppers, fire-roasted tomatoes, smoked paprika and ground beef. 

    Creamy Chicken, Mushroom & Spinach Skillet Casserole

    Photographer: Rachel Marek, Food Stylist: Annie Probst

    This spinach-packed casserole cooks on the stovetop and bakes in the same skillet for a family-friendly dinner with an easy cleanup. You can use leftover chicken and cook the pasta ahead of time to speed up the prep.

    Cheesy Meatball Casserole

    Photographer: Jen Causey, Food Stylist: Chelsea Zimmer, Prop Stylist: Julia Bayless

    This cheesy meatball casserole is a family favorite, with basil adding flavor to the meatballs and grated onion adding moisture. Melted mozzarella tames the spice, but feel free to cut back or eliminate the crushed red pepper if you prefer a milder dish.

    Buffalo Chicken & Cauliflower Casserole

    Jennifer Causey

    This creamy low-carb casserole is spicy and satisfying. Cauliflower and celery add a tender-crisp bite, while a sprinkle of blue cheese on top adds a savory finish.

    Jalapeño Popper Casserole

    Caitlin Bensel

    Jalapeño poppers, but make it a casserole! Here, we slather tender, juicy bites of chicken in a creamy, slightly spicy sauce with a crunchy topping of panko breadcrumbs and crispy bacon.

    Summer Vegetable Chicken Tortilla Casserole

    Devon O’Brien

    Summer’s harvest—eggplant, corn and zucchini—stars in this flavorful veggie casserole that’s perfect for serving a crowd or for a dinner with leftovers for the next day.

    Unstuffed Zucchini Casserole

    Photographer: Jen Causey, Food Stylist: Margaret Monroe Dickey, Prop Stylist: Hannah Greenwood.

    This hearty dinner takes all the flavors of classic stuffed zucchini and turns them into an easy casserole. Instead of hollowing and stuffing each zucchini, everything is layered in one dish for a quicker, no-fuss dinner. A sprinkle of shredded cheese on top melts into a bubbly, golden layer that ties it all together. This cozy casserole is perfect for a weeknight dinner and is an excellent way to use up summer zucchini.

    Creamy Chicken & Zucchini Casserole

    Photographer: Victor Protasio, Food Stylist: Chelsea Zimmer, Prop Stylist: Hannah Grennwood.

    This creamy chicken-and-zucchini casserole is a cozy dish that delivers all the flavors of cacio e pepe with a twist! Instead of pasta, tender chopped zucchini and juicy chicken pieces are folded into a peppery, cheesy sauce, bringing on all the savory flavors that fans of the classic Roman dish love. It’s a simple, crowd-pleasing meal that’s just as satisfying as a traditional creamy pasta dish.

    Bang Bang Chicken Casserole

    Photographer: Jen Causey, Food Stylist: Renu Dhar, Prop Stylist: Josh Hoggle

    Inspired by the popular Bonefish Grill Bang Bang Shrimp, this casserole combines tender, juicy chicken with crisp broccoli and nutty brown rice for a filling meal. The creamy casserole has the perfect balance of heat and sweetness, thanks to the sauce. Avoid stirring the chicken as it cooks or else the breading will fall off and the chicken won’t get crispy.

    Loaded Broccoli & Beef Casserole

    Photographer: Hannah Hufham, Food Stylist: Giovanni Vazquez, Prop Stylist: Abby Armstrong

    This loaded broccoli-and-beef casserole is packed with comforting flavors. Lean ground beef teams up with broccoli and brown rice to create a hearty, fiber-packed base with a creamy sauce. The highlight is the melted cheese on top—once broiled, it transforms into a golden, crispy layer that’s finished with bacon and scallions for the ultimate “loaded” experience. To keep prep simple, look for bags of pre-cut broccoli florets.

    Skillet Spinach, Mushroom & Wild Rice Casserole

    Photographer: Jen Causey, Food Stylist: Emily Nabors Hall, Prop Stylist: Julia Bayless

    This wild rice and mushroom casserole is the ultimate comfort food, combining hearty, wholesome ingredients with rich, savory flavors all in one skillet. The earthiness of the wild rice pairs beautifully with the meaty mushrooms, while fresh spinach adds a burst of color and nutrients. It’s the perfect balance of texture and taste—a cozy, one-pan meal that’s easy to make, which makes it even more comforting on those busy days!

    Marry Me Chicken & Spaghetti Squash Casserole

    Photographer: Jen Causey, Food Stylist: Emily Nabors Hall, Prop Stylist: Lindsey Lower

    This Marry Me chicken and spaghetti squash casserole is a satisfying protein-packed dinner. The tender chicken and nutrient-dense spaghetti squash deliver a hearty meal that will keep you full and energized. Sun-dried tomatoes add a burst of tangy sweetness, complementing the creamy sauce.

    Casseroles High Protein
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